News

Struggling with chronic constipation and overwhelmed by supplement claims? This comprehensive guide cuts through the guesswork, anchoring your choices in the 2023 AGA/ACG Clinical Practice Guideline: the top medical consensus.

We detail the Top 5 evidence-based natural supplements for constipation relief: Prunes, Kiwifruit, Psyllium Fiber, Magnesium Oxide, and Probiotics ($\text{B. lactis}$). The science is clear: Prunes and Kiwifruit beat psyllium in some head-to-head trials, while Magnesium Oxide offers powerful osmotic action ($70.6\%$ response in RCTs).

Learn our 5-Step Clinician Algorithm for safe, systematic care: when to start with a gentle food-based therapy, when to escalate to an osmotic agent like Magnesium Oxide, and critical safety caveats, including when to see a doctor. Get the evidence you need to take Let Loose with confidence.

Cold weather can throw your digestion out of whack. Learn the surprising link between the seasons and your stomach, and discover how Let Loose can be your winter companion for constipation relief and a happy gut.

New research from Harvard is changing how scientists think about what optimal digestion really looks like and the implications go far beyond just gut comfort

If you’ve looked into oxygen-based digestion supplements, you’ve probably seen names like Mag O7 and OxyPowder. They’re well-known—but not always meant for daily use. Here’s how they compare to a gentler option: the Let Loose Daily Capsules (Daily Capsules). The...

Your gut isn’t broken—it just needs the right mix of fuel and flow. What you eat plays a massive role in how smoothly things move through your system. Here’s a simple guide to the foods that help you poop, what...

Gut health isn’t about taking a dozen pills—it’s about a simple, effective foundation that supports your body’s natural rhythm. Here’s what to focus on, what actually works, and how to build a gut health stack that lasts. Step One: The...