Gut health that actually gets things moving.

Science-backed support for digestion, regularity, and everything in between.

Night #1 BestsellerLet Loose Daily Capsules bottle and tube

Where most people start

Daily Capsules

For Smooth, Stress-Free Poops

4.7 · 327 reviews

Oxygen-powered magnesium that relieves occasional constipation and bloating overnight — for smooth, stress-free poops, without cramping or dependency.*

From $48.60 $54.00
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Regularity starts with your whole gut

Build a healthier gut. Get more from your food. Keep waste moving. Different formulas, different jobs, one complete digestive routine.

Morning

Build Your Gut

Support your microbiome from the inside out.

Advanced Daily TrioBiotic: Complete Pre + Pro + Postbiotic Support

Every meal

Break Down Food

 Break it down. Absorb nutrients. Feel better after eating.

Koji Digestive Enzymes

Night

Move It Out

 Getting the good stuff in is only half the job.

A bottle and cylindrical box of Let Loose dietary supplement capsules on a solid teal background, with several blue-and-white capsules placed in front. Let Loose Lemonade Constipation Relief Drink Mix
Morning Advanced Daily TrioBiotic: Complete Pre + Pro + Postbiotic Support

Advanced Daily TrioBiotic

4.7 · 100 reviews

Build a healthier gut. Pre + pro + postbiotic support your microbiome over time, creating the foundation for better digestion, regularity and everything that comes next.*

From $50.40 $56.00
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Every meal Koji Digestive Enzymes

Koji Digestive Enzymes

4.9 · 76 reviews

Break down what goes in. 16 koji-fermented enzymes help digest food and unlock nutrients at every meal, so your body gets more from your food and your gut has less work to do afterward.*

From $50.40 $56.00
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Night A bottle and cylindrical box of Let Loose dietary supplement capsules on a solid teal background, with several blue-and-white capsules placed in front.

Daily Capsules

4.7 · 327 reviews

Move out what’s left. After food is broken down and nutrients are absorbed, oxygen-powered magnesium helps keep waste moving overnight for a gentle, complete bowel movement by morning.*

From $48.60 $54.00
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Night Let Loose Lemonade Constipation Relief Drink Mix

Let Loose Lemonade

4.9 · 32 reviews

Extra help when things get off track. Your zero-sugar, on-the-go backup for travel, period week, heavy meals or whenever you need more help getting things moving.*

From $31.50 $35.00
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Bundle & Save

Digestion isn’t just one thing, it’s a system. Our science-backed formulas are built to stack together

Let Loose Essentials Starter Kit

Essentials Starter Kit

The full day in one box — TrioBiotic for morning, Koji for meals, Daily Capsules for night.*

From $149.40 $166.00
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Round it out

Not part of the daily routine, but they make the rest of it better.

Pre-orderSH*T SHOES™

SH*T SHOES™

4.4 · 28 reviews

The chic way to sh*t. Elevate your knees. Align your colon. Unleash the flow.

$79.99
Flushable Wipes - For When You Let Loose

Flushable Wipes

Plant-based, flushable, and gentle where it counts. The finish to a job well done.

From $10.79 $11.99
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Real Relief, Real People, Real Reviews

They were backed up, bloated, and done feeling stuck. Here’s what happened after they Let Loose.